Clinical Studies

Hyaluronic Acid

1.

Weindl G, Schaller M, Schafer-Korting M, Korting HC

Hyaluronic acid in the treatment and prevention of skin diseases: molecular, biological, pharmaceutical and clinical aspects

Skin Pharmacol Physiol 2004; 17: 207–13.

https://pubmed.ncbi.nlm.nih.gov/15452406/

2.

Bravo B, Correia P, Euzébio Gonçalves Junior J, Sant’Anna B, Kerob D

Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence

Dermatologic Therapy, Wiley Open Access Collection

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078143/

3.

Nasir Abbas Bukhari S, Liyana Roswandi N, Muhammad W, Habib H

Hyaluronic Acid, a Promising Skin Rejuvenating Biomedicine: A Review of Recent Updates and Pre-clinical and Clinical Investigations on Cosmetic and Nutricosmetic Effects

International Journal of Biological Macromolecules

https://www.researchgate.net/publication/327952833_Hyaluronic_Acid_a_Promising_Skin_Rejuvenating_Biomedicine_A_Review_of_Recent_Updates_and_Pre-clinical_and_Clinical_Investigations_on_Cosmetic_and_Nutricosmetic_Effects

4.

Mraz Robinson D, Vega J, Palm MD, Bell M, Widgerow AD, Giannini A

Multicenter evaluation of a topical hyaluronic acid serum

Journal of Cosmetic Dermatology

https://onlinelibrary.wiley.com/doi/10.1111/jocd.15241

Vitamin C

5.

Traikovich SS

Use of Topical Ascorbic acid and its effects on Photo damaged skin topography 

Arch Otorhinol Head Neck Surg 1999;125:1091‐8

https://pubmed.ncbi.nlm.nih.gov/10522500/

6.

Humbert PG, Haftek M, Creidi P, et al
Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo
Exp Dermatol 2003;12:237–44.

https://pubmed.ncbi.nlm.nih.gov/12823436/

7.

Al-Niami F, Yi Zhen Chiang N

Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications

Journal of Clinical and Aesthetic Dermatology

https://jcadonline.com/topical-vitamin-c-and-the-skin-mechanisms-of-action-and-clinical-applications/

8.

Saokar Telang P

Vitamin C in dermatology

Indian Dermatology Online Journal

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673383/

9.

Correia G

Efficacy of topical vitamin C in melasma and photoaging: A systematic review

Journal of Cosmetic Dermatology

https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.15748

10.

Jaros-Sajda A, Budzisz E, Erkiert-Polguj A

Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin

Department of Cosmetic Raw Materials Chemistry, Faculty of Pharmacy, Medical University of Lodz

https://www.mdpi.com/2076-3921/13/2/174

11.

Michels A, Draelos Z

Vitamin C and Skin Health

Linus Pauling Institute, Oregon State University

https://lpi.oregonstate.edu/mic/health-disease/skin-health/vitamin-C

12.

Murray JC, Burch JA, Streilein RD, Iannacchione MA, Hall RP, Pinnell SR

A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation

Journal of the American Academy of Dermatology

https://www.sciencedirect.com/science/article/abs/pii/S0190962208005410

Ferulic Acid

13.

Zhang L, Al-Suwayeh SA, Hsieh P, Fang J

A comparison of skin delivery of ferulic acid and its derivatives: Evaluation of their efficacy and safety

International Journal of Pharmaceutics

https://www.sciencedirect.com/science/article/abs/pii/S0378517310005818

14.

Zdunska-Pęciak K, Dębowska R, Kołodziejczak A, Rotsztejn H

Ferulic acid – A novel topical agent in reducing signs of

photoaging

Dermatologic Therapy, Wiley Online Library

https://cnb.drirenaeris.com/wp-content/uploads/2022/12/FA-a-novel-agent.pdf

15.

Lin F, Lin J, Gupta RD, Tournas JA, Burch JA, Selim MA, Monteiro-Riviere NA, Grichnik JM, Zielinski J, Pinnell SR

Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin

Journal of Investigative Dermatology

https://pubmed.ncbi.nlm.nih.gov/16185284/

16.

Zdunska-Pęciak K, Kołodziejczak A, Rotsztejn H

Two superior antioxidants: Ferulic acid and ascorbic acid in reducing signs of photoaging—A split-face comparative study

Dermatologic Therapy, Wiley Online Library

https://onlinelibrary.wiley.com/doi/abs/10.1111/dth.15254

d-Alpha Tocopherol

17.

Michels A, Traber MG

Vitamin E and Skin Health

Linus Pauling Institute, Oregon State University

https://lpi.oregonstate.edu/mic/health-disease/skin-health/vitamin-E

18.

Pinto CASO, Martins TEA, Martinez RM, Freire TB, Velasco MVR, and Baby AR

Vitamin E in Human Skin: Functionality and Topical Products

Vitamin E in Health and Disease, IntechOpen

https://www.intechopen.com/chapters/77087