Clinical Studies

Hyaluronic Acid


Weindl G, Schaller M, Schafer-Korting M, Korting HC

Hyaluronic acid in the treatment and prevention of skin diseases: molecular, biological, pharmaceutical and clinical aspects

Skin Pharmacol Physiol 2004; 17: 207–13.


Bravo B, Correia P, Euzébio Gonçalves Junior J, Sant’Anna B, Kerob D

Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence

Dermatologic Therapy, Wiley Open Access Collection


Nasir Abbas Bukhari S, Liyana Roswandi N, Muhammad W, Habib H

Hyaluronic Acid, a Promising Skin Rejuvenating Biomedicine: A Review of Recent Updates and Pre-clinical and Clinical Investigations on Cosmetic and Nutricosmetic Effects

International Journal of Biological Macromolecules


Mraz Robinson D, Vega J, Palm MD, Bell M, Widgerow AD, Giannini A

Multicenter evaluation of a topical hyaluronic acid serum

Journal of Cosmetic Dermatology

Vitamin C


Traikovich SS

Use of Topical Ascorbic acid and its effects on Photo damaged skin topography 

Arch Otorhinol Head Neck Surg 1999;125:1091‐8


Humbert PG, Haftek M, Creidi P, et al
Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo
Exp Dermatol 2003;12:237–44.


Al-Niami F, Yi Zhen Chiang N

Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications

Journal of Clinical and Aesthetic Dermatology


Saokar Telang P

Vitamin C in dermatology

Indian Dermatology Online Journal


Correia G

Efficacy of topical vitamin C in melasma and photoaging: A systematic review

Journal of Cosmetic Dermatology


Jaros-Sajda A, Budzisz E, Erkiert-Polguj A

Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin

Department of Cosmetic Raw Materials Chemistry, Faculty of Pharmacy, Medical University of Lodz


Michels A, Draelos Z

Vitamin C and Skin Health

Linus Pauling Institute, Oregon State University


Murray JC, Burch JA, Streilein RD, Iannacchione MA, Hall RP, Pinnell SR

A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation

Journal of the American Academy of Dermatology

Ferulic Acid


Zhang L, Al-Suwayeh SA, Hsieh P, Fang J

A comparison of skin delivery of ferulic acid and its derivatives: Evaluation of their efficacy and safety

International Journal of Pharmaceutics


Zdunska-Pęciak K, Dębowska R, Kołodziejczak A, Rotsztejn H

Ferulic acid – A novel topical agent in reducing signs of


Dermatologic Therapy, Wiley Online Library


Lin F, Lin J, Gupta RD, Tournas JA, Burch JA, Selim MA, Monteiro-Riviere NA, Grichnik JM, Zielinski J, Pinnell SR

Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin

Journal of Investigative Dermatology


Zdunska-Pęciak K, Kołodziejczak A, Rotsztejn H

Two superior antioxidants: Ferulic acid and ascorbic acid in reducing signs of photoaging—A split-face comparative study

Dermatologic Therapy, Wiley Online Library

d-Alpha Tocopherol


Michels A, Traber MG

Vitamin E and Skin Health

Linus Pauling Institute, Oregon State University


Pinto CASO, Martins TEA, Martinez RM, Freire TB, Velasco MVR, and Baby AR

Vitamin E in Human Skin: Functionality and Topical Products

Vitamin E in Health and Disease, IntechOpen